Once upon a time, women were drowned in the river and the only witnesses were the crows in the trees. The Puritans blamed Eve for the sins of the world. That was when we began to meet in the name of Lilith, Adam's first wife—banished for refusing to do as she was told.

By the 1950s, Cambridge, Massachusetts feels far removed from the legendary witch trials that marked its early days as a colony. Ava, a bright young woman from a small town in Maine, arrives for her first year at Radcliffe college. There, she meets Lauren, her opposite in every way—the wild and brazen daughter of a wealthy and well established Cambridge family. But the two have more in common than they think. Both are recruited by the Lilith Society, a secret organization of witches at Radcliffe dating back to colonial times. As they learn more about their legacy, Ava and Lauren form a close bond that is put to the test as they learn to navigate their new power, friendship, and love.

While Radcliffe seems like a safe haven, the shadow of McCarthyism looms large, an ever-present threat to the flourishing creative and intellectual life in Cambridge. And as girls from the Lilith Society begin to go missing, Ava and Lauren realize the witch trials of the past may not be as deeply buried as they once believed.